The Prevalence of Autoimmune Diseases in Women and the Role of Exercise in Management
- Naima Smith

- Oct 28
- 5 min read
Autoimmune diseases are so common that if you yourself do not have one, you probably have someone in your life who is affected by one. For me, it's my grandmother. Growing up, I watched her manage her Lupus diagnosis. It affected her energy levels and appetite, but she used exercise to help with the symptoms. Because of her amazing management of the disease, she is 96 years old and is just now slowing down, showing us it's possible to live a full life despite a diagnosis.
Autoimmune diseases are disorders where the immune system mistakenly attacks the body’s own tissues. These conditions primarily affect women, with research indicating that about 75% of individuals diagnosed with autoimmune diseases are female. In this blog post, we will explore the prevalence of autoimmune diseases in women and how exercise can play a critical role in managing these conditions.

Understanding Autoimmune Diseases
Autoimmune diseases include a wide range of conditions, such as lupus, rheumatoid arthritis, multiple sclerosis, and Hashimoto's thyroiditis. While the exact cause remains unclear, several factors contribute to their development, including genetic, environmental, and hormonal influences.
Women have a higher susceptibility to autoimmune diseases due to hormonal differences, specifically the effects of estrogen. Studies suggest that estrogen may alter immune system functioning, potentially increasing the risk of autoimmune disorders in women. There is also some evidence that suppressing negative emotions, such as anger, sadness, can exacerbate the disease.
Symptoms of autoimmune diseases can differ widely, from fatigue and joint pain to serious complications impacting various organs. This variability often complicates diagnosis, leading to delays in treatment and proper management.
The Prevalence of Autoimmune Diseases in Women
The statistics surrounding autoimmune diseases in women are troubling. According to the American Autoimmune Related Diseases Association (AARDA), autoimmune diseases rank among the top 10 leading causes of death for women under 65. Conditions such as lupus and rheumatoid arthritis impact millions of women globally, with rheumatoid arthritis alone affecting approximately 1.5 million Americans.
The reasons behind this gender imbalance are multifaceted. Hormonal fluctuations throughout a woman's life—specifically during menstruation, pregnancy, and menopause—can worsen symptoms and influence how diseases progress. On top of this, factors such as stress and lifestyle choices may greatly affect women's vulnerability to these illnesses.

The Role of Exercise in Managing Autoimmune Diseases
As we see with my grandmother, exercise can be a game-changer in managing autoimmune diseases. Regular physical activity provides numerous benefits, including symptom relief, improved health, and enhanced quality of life. Here is how exercise can support women with autoimmune diseases:
1. Reducing Inflammation
Regular exercise can help diminish inflammation, a common issue for those living with autoimmune diseases. Engaging in physical activity has shown reductions in markers like C-reactive protein (CRP), potentially leading to fewer flare-ups. For instance, a study found that consistent exercise reduced CRP levels by 30% in participants with rheumatoid arthritis.
2. Enhancing Mood and Mental Health
The stress of living with an autoimmune disease can affect mental well-being. Exercise has been proven to release endorphins, which can elevate mood and diminish anxiety and depression. Walking for even 30 minutes a day can make a notable difference, helping those managing these chronic conditions feel more optimistic and in control.
3. Improving Physical Function and Strength
Autoimmune diseases often lead to muscle weakness and fatigue. Regular exercise improves physical function, boosts strength, and enhances endurance. For women, this is crucial for maintaining independence and participation in daily activities. Studies show that strength training can increase muscle mass by 3-8% in those with chronic conditions over a period of just 12 weeks.
4. Promoting Better Sleep
Many individuals with autoimmune diseases face sleep disruptions. Regular physical activity can help regulate sleep patterns, leading to better quality rest. Improved sleep not only helps combat fatigue but also enhances emotional well-being, which is vital for overall health.
5. Building a Supportive Community
Participating in group exercise classes or community sports can provide valuable social support, which is critical for managing mental health. Connecting with others who understand the challenges of living with autoimmune diseases fosters a sense of community and encouragement. For example, joining a local walking group can not only provide fitness benefits but also build lasting friendships.
Types of Exercise Beneficial for Women with Autoimmune Diseases
Not all forms of exercise are suitable for women managing autoimmune diseases. Below are recommended types that can be especially beneficial:
1. Low-Impact Aerobic Exercises
Activities like walking, swimming, and cycling are excellent choices. These low-impact exercises can enhance cardiovascular health without putting excessive strain on the joints. A study indicated that women with rheumatoid arthritis who engaged in regular low-impact aerobic exercise reported a 40% reduction in pain.
2. Strength Training

Incorporating strength training into a fitness routine builds muscle and improves overall strength. Using resistance bands or light weights can be particularly effective and safe. A program including strength training can significantly increase functional independence for women with autoimmune disorders.
3. Flexibility and Balance Exercises
Yoga and Pilates are fantastic for improving flexibility and balance while also promoting relaxation and stress relief. These practices have been shown to decrease levels of stress hormones, making them ideal for women facing the emotional strain of autoimmune diseases.
4. Mind-Body Exercises
Mind-body exercises such as tai chi and qigong focus on gentle movements and breathing. These practices can enhance mental clarity and decrease stress, which is particularly advantageous for women managing autoimmune conditions.

Tips for Starting an Exercise Routine
Starting a new exercise routine can feel overwhelming, especially for those living with autoimmune diseases. Here are some helpful tips:
1. Consult with a Healthcare Provider
Before embarking on any exercise program, it’s important to discuss plans with a healthcare provider. They can give tailored recommendations based on individual health needs and limitations.
2. Start Slow and Listen to Your Body
Beginning slowly and gradually increasing workout intensity and duration is vital. Recognizing when to rest is equally important to avoid overexertion or injury.
3. Set Realistic Goals
Setting achievable fitness goals helps maintain motivation. Whether it's walking for 10 minutes or attending a weekly yoga class, starting small can lead to significant progress over time.
4. Find Enjoyable Activities
Choosing activities that are enjoyable makes exercise feel less like a chore. Whether it’s dancing, hiking, or joining a group class, it’s beneficial to find joy in movement.
5. Stay Consistent
Consistency is crucial for truly benefiting from exercise. Establishing a regular workout schedule fosters habit formation and helps maintain an active lifestyle in the long run.
Empowering Health through Exercise
Autoimmune diseases impact many women’s lives, but exercise offers a powerful way to manage these conditions. By reducing inflammation, boosting mood, and improving physical function, regular physical activity can enhance the quality of life for those affected.
As women confront the challenges posed by autoimmune diseases, incorporating exercise into their daily lives fosters not only physical health but also emotional support and community connection. With the right strategies, women can reclaim their health, empowering themselves to overcome the challenges of autoimmune diseases and live fulfilling lives.
By recognizing the prevalence of autoimmune diseases and understanding the role of exercise in management, we can create a supportive ecosystem that encourages active lifestyles and holistic well-being.
Let me know your thoughts in the comments! Do you know anyone with an autoimmune disease?
Best in Health,
Coach Nai




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